The seismogenic fault and the dynamic mechanism of the Ning’er, Yunnan Province MS6.4 earthquake of June 3, 2007 are studied on the basis of the observation data of the surface fissures, sand blow and water eruption, land-slide and collapse associated with the earthquake, incorporating with the data of geologic structures, focal mecha-nism solutions and aftershock distribution for the earthquake area. The observation of the surface fissures reveals that the Banhai segment of the NW-trending Ning’er fault is dominated by right-lateral strike-slip, while the NNE-trending fault is dominated by left-lateral strike-slip. The seismo-geologic hazards are concentrated mainly within a 330°-extending zone of 13.5 km in length and 4 km in width. The major axis of the isoseismal is also oriented in 330° direction, and the major axis of the seismic intensity VIII area is 13.5 km long. The focal mechanism solutions indicate that the NW-trending nodal plane of the Ning’er MS6.4 earthquake is dominated by right-lateral slip, while the NE-trending nodal plane is dominated by left-lateral slip. The preferred distribution orientation of the aftershocks of MS≥2 is 330°, and the focal depths are within the range of 3~12 km, predominantly within 3~10 km. The distribution of the aftershocks is consistent with the distribution zone of the seismo-geologic hazards. All the above-mentioned data indicate that the Banhai segment of the Ning’er fault is the seismogenic fault of this earthquake. Moreover, the driving force of the Ning’er earthquake is discussed in the light of the active block theory. It is believed that the northward pushing of the Indian plate has caused the eastward slipping of the Qinghai-Tibetan Plateau, which has been transformed into the southeastern-southernward squeezing of the southwest Yunnan region. As a result, the NW-trending faults in the vicinity of the Ning’er area are dominated by right-lateral strike-slip, while the NE-trending faults are dominated by left-lateral strike-slip. This tectonic framework might be the main cause of the frequent occurrence of MS6.0~6.9 earthquakes in the area. The seismogenic fault and the dynamic mechanism of the Ning’er, Yunnan Province MS6.4 earthquake of June 3, 2007 are studied on the basis of the observation data of the surface fissures, sand blow and water eruption, land-slide and collapse associated with the earthquake, incorporating with the data of geologic structures, focal mecha-nism solutions and aftershock distribution for the earthquake area. The observation of the surface fissures reveals that the Banhai segment of the NW-trending Ning’er fault is dominated by right- lateral strike-slip, while the NNE-trending fault is dominated by left-lateral strike-slip. The seismo-geologic hazards are concentrated mainly within a 330 ° -extending zone of 13.5 km in length and 4 km in width. The major axis of the isoseismal is also oriented in 330 ° direction, and the major axis of the seismic intensity VIII area is 13.5 km long. The focal mechanism solutions indicate that the NW-trending nodal plane of the Ning’er MS6.4 earthquake is dominated by right-lateral slip while the NE-trending nodal plane is dominated by left-lateral slip. The preferred distribution orientation of the aftershocks of MS ≧ 2 is 330 ° and the focal depths are within the range of 3 ~ 12 km , predominantly within 3 ~ 10 km. The distribution of the aftershocks is consistent with the distribution zone of the seismo-geologic hazards. All the above-mentioned data indicate that the Banhai segment of the Ning’er fault is the seismogenic fault of this earthquake The driving force of the Ning’er earthquake is discussed in the light of the active block theory. It is believed that the northward pushing of the indium plate has caused the eastward slipping of the Qinghai-Tibetan Plateau, which has been transformed. into the southeastern-southernward squeezing of the southwest Yunnan region. As a result, the NW-trending faults in the vicinity of the Ning’er area are dominated by right-lateral strike-slip, while the NE-trending faults are domin ated by left-lateral strike-slip. This tectonic framework might be the main cause of the frequent occurrence of MS6.0 ~ 6.9 earthquakes in the area.