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目的:优选心痛舒片提取工艺。方法:以单因素对乙醇浓度进行考察后,采用正交试验设计法考察溶剂量、浸泡时间及提取时间3个因素对丹参酮Ⅱ_A得率的影响。结果:优选出最佳提取工艺为:乙醇浓度90%,提取两次,溶媒量分别为8倍、6倍,浸泡1.5 h,分别提取1.5 h、1.0 h。结论:上述试验结果可为心痛舒片提取工艺提供试验依据。
Objective: To optimize the process of extraction of Xintong Shu tablet. Methods: After investigating ethanol concentration by single factor, orthogonal design was used to investigate the influence of solvent quantity, soaking time and extraction time on the yield of tanshinone Ⅱ A. Results: The optimal extraction process was as follows: the concentration of ethanol was 90%, extracted twice, the amount of solvent was 8 times and 6 times respectively, soaked for 1.5 h and extracted for 1.5 h and 1.0 h respectively. Conclusion: The above test results provide the experimental basis for the extraction process of Xintong Shu tablet.