论文部分内容阅读
目的研究亚临床甲状腺功能减退症(subclinical hypothyroidism,SH)与冠心病的相关性。方法选取2013年1月~2014年2月广东省英德市人民医院收入的行冠状动脉造影的患者120例,以结果为依据分为2组。对照组62例,观察组58例,将观察组可分为多支病变组(n=28)与单支病变组(n=30)。检查患者的TG(三酰甘油)、TC(总胆固醇)、FT4、FT3、sTSH、LDL-C、HDL-C、ApoA 1、ApoB、Fbg水平变化情况。结果观察组发生甲状腺功能减退症的患者数量明显高于对照组,差异有统计学意义(P<0.05);观察组的sTSH水平高于对照组,单支病变组的sTSH水平低于多支病变组,差异有统计学意义(P<0.05);观察组ApoB与总胆固醇水平高于对照组,差异有统计学意义(P<0.05)。结论 SH(亚临床甲状腺功能减退症)发生冠心病的风险较高,是诱发冠心病的相关因素之一。
Objective To study the relationship between subclinical hypothyroidism (SH) and coronary heart disease. Methods A total of 120 patients undergoing coronary angiography from January 2013 to February 2014 in Yingde People’s Hospital of Guangdong Province were selected and divided into two groups based on the results. Control group, 62 cases, observation group, 58 cases, the observation group can be divided into multi-vessel disease group (n = 28) and single vessel disease group (n = 30). The levels of TG, triglyceride, total cholesterol, FT4, FT3, sTSH, LDL-C, HDL-C, ApoA1, ApoB and Fbg in patients were examined. Results The number of patients with hypothyroidism in the observation group was significantly higher than that in the control group (P <0.05). The sTSH level in the observation group was higher than that in the control group. The sTSH level in the single-vessel lesion group was lower than that in the multi-vessel disease group (P <0.05). The levels of ApoB and total cholesterol in the observation group were higher than those in the control group, with significant difference (P <0.05). Conclusion SH (subclinical hypothyroidism) is associated with a higher risk of coronary heart disease, which is one of the relevant factors in inducing coronary heart disease.