论文部分内容阅读
胆固醇水平降低可能限制肿瘤生长或者转移所需的细胞增殖。该研究假设,在癌症诊断之前使用他汀治疗,与癌症相关死亡率降低相关。该研究评估1995-2007年丹麦总人口中诊断为癌症(随访至2009-11-31)的患者的死亡率。在≥40岁的患者中,18721例患者在癌症诊断前就有规律地服用他汀类药物(他汀组),而277204例从未使用他汀类药物(非他汀组)。研究结果显示,多因素变量调整后,与非他汀组比较,他汀
Decreased cholesterol levels may limit the cell proliferation required for tumor growth or metastasis. The study hypothesized that the use of statin therapy prior to cancer diagnosis was associated with reduced cancer-related mortality. This study assessed the mortality rate of patients diagnosed with cancer (follow-up to 2009-11-31) in the Danish population from 1995 to 2007. Among patients > 40 years of age, 18,721 patients regularly take statin drugs (statins group) before the diagnosis of cancer, while 277,204 patients never use statin drugs (non-statin group). The results of the study showed that after adjustment for multivariate variables, statin was compared with non-statin group