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近年来,有关自身免疫病的研究进展较快,对自身免疫反应的认识也趋深化。实际上,自身免疫反应系机体的正常防御机能之一,体内出现自身抗体并不一定有病,例如α—甲基多巴治疗后,10~30%患者的血抗红细胞抗体阳性,然而发生溶血性贫血者仅为1~2%。正常人体出现自家抗体,多系免疫系统为清除衰老和变异的细胞以保持生理稳定所产生的防御机能之一,尤其是60岁以上者,其抗核抗体、类风湿因子阳性率更高,却并不发病。但若由
In recent years, research on autoimmune diseases has progressed rapidly, and awareness of the autoimmune response has also deepened. In fact, the autoimmune response is one of the normal defensive functions of the body, autoantibodies are not necessarily present in the body. For example, 10-30% of the patients have anti-erythrocytic antibodies after treatment with α-methyldopa, however, hemolysis occurs Anemia were only 1 to 2%. Normal human body appears their own antibodies, multi-line immune system for the removal of aging and mutation of cells to maintain the physiological stability of the defensive function produced, especially over the age of 60, the anti-nuclear antibodies, rheumatoid factor positive rate is higher, Not disease. But if by