细胞凋亡的概念首先由Kerr等于1972年提出。多年来随着细胞凋亡及其机制不断深入的研究,人们发现,肿瘤的发生可能由细胞增殖与凋亡的速度平衡失调造成;失调的程度可决定肿瘤发展的速度。目前,很多学者通过促进癌细胞凋亡来治疗肿瘤,同时也发现许多抗肿瘤药物杀伤肿瘤细胞是通过 The concept of apoptosis was first proposed by Kerr et al. In 1972. Over the years, with the continuous research of cell apoptosis and its mechanism, it has been found that the occurrence of tumor may be caused by the imbalance of the rate of cell proliferation and apoptosis; the degree of disorder can determine the speed of tumor development. At present, many scholars treat cancer by promoting apoptosis of cancer cells, and also find that many anti-tumor drugs kill tumor cells by