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目的对食管癌术后发生胃排空障碍的病例进行单中心分析,总结其发生原因和诊治经验。方法回顾性分析第二军医大学长征医院2003年1月至2012年12月间1 294例食管癌患者的病例资料,将其中发生胃排空障碍的19例(1.47%)患者作为观察组,未发生胃排空障碍的1 275例作为对照组。比较两组患者年龄、糖尿病史、吻合部位、手术入路及游离胃方式等,分析可能影响胃排空障碍发生的因素。通过本中心的研究得出胃排空障碍发生规律和治疗手段。结果术后发生胃排空障碍的19例患者经保守治疗均痊愈。经单因素分析显示,胃排空障碍的发生与患者的年龄、糖尿病史、吻合部位、手术入路和游离胃方式均无关(P>0.05)。结论食管癌术后胃排空障碍发生率低,发生原因不明确,一旦发生则严重影响患者的生活质量,但经保守治疗均可恢复。
Objective To analyze single-center case of gastric emptying disorder after esophageal cancer surgery and summarize its causes and diagnosis and treatment experience. Methods The data of 1 294 esophageal cancer patients from January 2003 to December 2012 in Changzheng Hospital of the Second Military Medical University were retrospectively analyzed. 19 (1.47%) patients with gastric emptying disorder were considered as observation group, There were 1 275 cases of gastric emptying disorder as control group. The age, history of diabetes mellitus, anastomotic sites, surgical access and free stomach were compared between the two groups to analyze the factors that may affect the occurrence of gastric emptying disorder. Through the center’s research drawn gastric emptying disorder and treatment. Results 19 cases of gastric emptying disorder after conservative treatment were cured. Univariate analysis showed that the occurrence of gastric emptying disorder had no relation with the patient’s age, history of diabetes, site of anastomosis, surgical access and free stomach (P> 0.05). Conclusion The incidence of gastric emptying after esophageal cancer surgery is low, the cause is not clear, in the event of serious impact on the quality of life of patients, but conservative treatment can be restored.