The project of Xiaoxihu Yellow River Bridge in Lanzhou is chosen as partial cable-stayed bridge. To get the shear lag effect and anti-earthquake performance of the actual bridge under various loading conditions, organic glass scaled model was adopted to have an experiment and a theory research at one time. The experiment result is the basically same as the theory calculation which proves the FEA method can well calculate shear lag effect and dynamical performance. As a result, because the bridge is located in a seismic area of 8 degree, an elasto-plastic seismic checking is performed by customized FEA program in this paper.