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目的探讨针对癫痫患儿采用拉莫三嗪治疗与整体护理的有效性与安全性。方法癫痫患儿84例,随机分为实验组与对照组,每组42例,实验组给予拉莫三嗪联合整体护理措施,对照组给予丙戊酸钠与整体护理措施。对比两组患儿总有效率及不良反应发生率。结果实验组患儿总有效率为95.24%,不良反应发生率为4.76%,均显著优于对照组的78.57%、16.67%,差异具有统计学意义(P<0.05)。结论针对癫痫患儿给予拉莫三嗪联合整体护理措施可显著抑制症状发作。
Objective To investigate the efficacy and safety of lamotrigine for general anesthesia in children with epilepsy. Methods Eighty-four children with epilepsy were randomly divided into experimental group and control group, with 42 cases in each group. The experimental group was treated with lamotrigine in combination with the overall nursing measures while the control group with sodium valproate and the overall nursing measures. The total effective rate and the incidence of adverse reactions in both groups were compared. Results The total effective rate was 95.24% in the experimental group and 4.76% in the adverse reaction group, which were significantly better than 78.57% and 16.67% of the control group, respectively. The difference was statistically significant (P <0.05). Conclusion The combination of lamotrigine and the overall nursing measures for children with epilepsy can significantly inhibit the onset of symptoms.