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目的观察自拟解毒凉血汤灌肠联合美沙拉嗪栓治疗直肠型溃疡性结肠炎的临床效果。方法收集医院接诊的患直肠型溃疡性结肠炎患者150例,随机分为研究组和对照组各75例:对照组给予甲硝唑灌肠与美沙拉嗪栓联合治疗;研究组给予自拟解毒凉血汤灌肠与美沙拉嗪栓联合治疗。观察及比较2组的临床治疗效果。结果研究组总有效率为98.67%明显高于对照组的80.00%(P<0.05)。研究组治疗后的PLT与ESR均明显低于治疗前,且低于对照组治疗后,差异均有统计学意义(P<0.05)。结论对直肠型溃疡性结肠炎患者采用自拟解毒凉血汤灌肠与美沙拉嗪栓联合治疗疗效显著,可有效缓解患者的炎症反应。
Objective To observe the clinical effect of self-detoxification and cooling blood soup enema combined with Mesalazine suppository in the treatment of rectal ulcerative colitis. Methods A total of 150 patients with rectal ulcerative colitis admitted to the hospital were collected and randomly divided into study group (75 cases) and control group (75 cases). The control group was given metronidazole enema combined with mesalamine suppository. The study group was given detoxification Cooling blood soup enema and mesalamine suppository combination therapy. Observation and comparison of two groups of clinical treatment. Results The total effective rate of the study group was 98.67%, which was significantly higher than that of the control group (80.00%, P <0.05). The PLT and ESR of the study group after treatment were significantly lower than before treatment, and lower than the control group after treatment, the difference was statistically significant (P <0.05). Conclusions The treatment of rectal ulcerative colitis patients with self-detoxification and cooling blood soup enema and mesalamine suppository have a significant effect, which can effectively relieve the patient’s inflammatory response.