缺血性脑卒中是病死率和致残率较高的中枢神经系统疾病之一。脑卒中后局部及全身免疫系统的改变对脑卒中患者预后的影响日渐受到重视。脑卒中后存在免疫激活和免疫抑制,炎症反应可以清除坏死组织,但过度的炎症反应会导致继发性损伤;免疫抑制可能具有神经保护作用,但增加了感染的机会~[1]。Prass等~[2]认为脑卒中诱导的免疫抑制 Ischemic stroke is one of the central nervous system diseases with high mortality and morbidity. The impact of local and systemic immune system changes after stroke on the prognosis of stroke patients is receiving more and more attention. Post-stroke immune activation and immunosuppression, inflammation can clear necrotic tissue, but excessive inflammation can lead to secondary damage; immunosuppression may have neuroprotective effects, but increased the chance of infection [1]. Prass et al [2] that stroke-induced immune suppression