【摘 要】
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Brain injury, especially that caused by stroke, is a leading cause of mor-bidity and mortality worldwide. Numerous studies on the neuropro-tective effects of ne
【机 构】
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Department of Neurosurgery, Lanzhou University Second Hospital, Lanzhou, Gansu Province, China
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Brain injury, especially that caused by stroke, is a leading cause of mor-bidity and mortality worldwide. Numerous studies on the neuropro-tective effects of neural stem cells (NSCs) after brain injury have shown that crosstalk among neural cells, including neuron–glial, glial–glial, NSC–neuronal and NSC–glial communication, plays a major role in post-injury repair. Therefore, a better understanding of the factors in-volved in the interactions between NSCs and other neural cells should advance the development of therapeutic strategies for brain injury. In this article, we discuss the role of exosomes in the crosstalk between NSCs and microglia, focusing on key exosomal proteins and microR-NAs in brain injury progression and repair.
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