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目的探讨一种快速诊断住院患儿呼吸道肺炎衣原体感染的方法。方法应用直接免疫荧光法,对因呼吸道感染而住院的婴幼儿鼻咽部分泌物肺炎衣原体抗原进行检测。结果 1022例婴幼儿中有82例肺炎衣原体检测阳性,阳性率为8.02%,其中男62例,阳性率为9.23%,女20例,阳性率为5.71%,差异有统计学意义(χ2=3.85,P<0.05);从年龄分布情况看,12～24月的婴幼儿感染率最高,达14.77%;4-6月为肺炎衣原体的高发季节,检出阳性率为12.74%。结论肺炎衣原体是婴幼儿呼吸道感染的重要病原体之一,应用直接免疫荧光法可以直接、快速对其进行诊断。
Objective To explore a method for rapid diagnosis of respiratory Chlamydia pneumoniae infection in hospitalized children. Methods Direct immunofluorescence assay was used to detect the nasopharyngeal secretions of Chlamydia pneumoniae in infants with respiratory tract infection. Results Among 1022 infants and young children, 82 cases were positive for Chlamydia pneumoniae. The positive rate was 8.02%, of which 62 cases were male, the positive rate was 9.23% and the female was 20 cases, the positive rate was 5.71%, the difference was statistically significant (χ2 = 3.85 , P <0.05). According to the distribution of age, the highest infection rate was 14.77% in 12-24 months. The highest incidence of Chlamydia pneumoniae was found in April-June. The positive rate was 12.74%. Conclusion Chlamydia pneumoniae is one of the most important pathogens of respiratory tract infection in infants and young children. Direct immunofluorescence assay can be used to diagnose it directly and rapidly.