论文部分内容阅读
目的 :初步探讨幽门螺杆菌 (Hp)感染和胃癌发生的相关性。方法 :应用快速尿素酶实验、组织学和分子生物学方法联合检测 6 5例胃粘膜活检标本中 Hp感染。结果 :胃癌组织中 Hp的检出率显著高于正常组 ,Hp感染与患者年龄、性别无关。结论 :Hp可能在从浅表性胃炎→肠化生→不典型增生→胃癌的发生过程中起一定作用
Objective: To investigate the relationship between Helicobacter pylori (Hp) infection and gastric carcinogenesis. Methods: Rapid urease test, histological and molecular biological methods combined detection of Hp infection in 65 cases of gastric mucosal biopsy specimens. Results: The detection rate of Hp in gastric cancer tissues was significantly higher than that in normal controls. Hp infection was not related to age and sex of patients. Conclusion: Hp may play a role in the pathogenesis of superficial gastritis → intestinal metaplasia → dysplasia → gastric cancer