用六亚甲基二乙酰胺（ＨＭＢＡ）作为分化诱导剂，对人粘液表皮样癌细胞系ＭＥＣ－１细胞中角蛋白进行染色，结果发现高分子量角蛋白在被诱导细胞中含量明显增高。分光光度仪检测角蛋白含量，诱导组ｘ±ｓ为２１８±５１，对照组为１４９±４７，两组有显著差异（Ｐ＜００１），这可能与细胞分化有关。 Using hexamethylene bisacetamide (HMBA) as a differentiation inducer to stain keratin in human mucoepidermoid carcinoma cell line MEC-1 cells, it was found that the content of high molecular weight keratin was significantly increased in the induced cells. The keratin content was measured by spectrophotometer. The x±s in the induction group was 218±51, and that in the control group was 149±47. There was a significant difference between the two groups (P<001). This may be related to the cells. Differentiation related.