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粒细胞集落刺激因子(G-CSF)是一种造血生长因子,最开始被用于治疗粒细胞减少症等血液系统疾病,目前越来越多的研究证明G-CSF在缺血性脑梗死中能发挥强大的神经保护效应。该文就其作用机制及其在临床应用中的一些研究进展予以综述。
Granulocyte colony-stimulating factor (G-CSF) is a hematopoietic growth factor that was initially used to treat hematological diseases such as neutropenia. More and more studies have shown that G-CSF is effective in ischemic stroke Can play a powerful neuroprotective effect. This article reviews its mechanism of action and its progress in clinical application.