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目的探讨阿昔洛韦与常用药物配伍的稳定性,为临床合理用药提供依据。方法在“知网”、“维普”及“万方”等数据库在线检索2006-2016年国内医学期间公开发表的阿昔洛韦与常用药物的配伍资料,进行归纳整理。分析阿昔洛韦与常用药物配伍的稳定性。结果阿昔洛韦和酚磺乙胺、多巴胺、10%果糖二磷酸钠及右旋糖酐40葡萄糖注射液因理化性质改变而不可进行配伍。结论阿昔洛韦与多数常用药物均能根据一定的剂量进行配伍,且在一定时间、温度范围内相对稳定,但仍与部分药物不宜配伍,应根据情况合理用药。
Objective To investigate the stability of compatibility of acyclovir with commonly used drugs and provide the basis for clinical rational drug use. Methods The databases of acyclovir and commonly used drugs published during the period of domestic medicine from 2006 to 2016 were searched online in databases such as Knowledge Network, Weipu and Wanfang for summarization. Analysis of the stability of compatibility of acyclovir with commonly used drugs. Results acyclovir and phenylethylamine, dopamine, 10% sodium fructose diphosphate and dextran 40 glucose injection due to changes in physical and chemical properties can not be compatible. Conclusion Acyclovir and most commonly used drugs can be based on a certain dose compatibility, and in a certain period of time, the temperature range is relatively stable, but still with some drugs should not be compatible, should be based on the rational use of drugs.