论文部分内容阅读
采用酶联免疫吸附法在１５７例反复呼吸道感染（ＲＲＴＩ）儿童中检测出血清ＩｇＧ＿２缺陷１５例；同时发现肺炎球菌多糖抗原（ＰｎＰｇ）特异性ＩｇＧ＿２抗体缺陷２６例，其中９例同时伴血清ＩｇＧ＿２缺陷，占１５例血清ＩｇＧ＿２缺陷者的６０％；脑膜炎球菌多糖抗原（ＭＰｓ）特异性ＩｇＧ＿２抗体缺陷２０例，其中１１例同时伴血清ＩｇＧ＿２缺陷。占１５例血清ＩｇＧ＿２缺陷者的７３％。本文提示：血清多糖抗原特异性ＩｇＧ亚类抗体缺陷是儿童ＲＲＴＩ的重要原因之一；血清ＩｇＧ＿２正常并不能排除多糖抗原特异性ＩｇＧ＿２抗体缺陷。
Serum IgG_2 deficiency was detected in 15 children with recurrent respiratory tract infection (RRTI) by enzyme-linked immunosorbent assay (ELISA) in 15 cases. Meanwhile, 26 cases of PnPg-specific IgG_2 antibody deficiency were found in 26 cases, of which 9 cases were accompanied with serum IgG_2 deficiency , Accounting for 60% of 15 IgG2-deficient serums; 20 cases of IgG2-specific antibodies against meningococcal polysaccharide antigen (MPs), of which 11 cases were associated with serum IgG2 deficiency. Accounting for 73% of IgG2-deficient patients in 15 cases. This article suggests that: Serum polysaccharide antigen-specific IgG subclass antibody defects is one of the important reasons for RRTI in children; serum IgG_2 normal and can not rule out polysaccharide antigen-specific IgG 2 antibody defects.