生长激素(GH)对儿童的正常生长发育起重要作用。一般而言,GH缺乏的儿童均有发育迟缓。目前,诊断GH缺乏的标准方法是应用放射免疫法(RIA)测定患儿血浆GH水平,如基础的和激发状态下的GH浓度均低于正常值,结合临床,大致可以确诊。本文报告4名儿童(6～13岁),其中1名患肢端肥大症,RIA证实GH缺乏,但其骨龄、身高、体重以及年生长率(5.8～8 cm Growth hormone (GH) plays an important role in children’s normal growth and development. In general, GH-deficient children have stunting. At present, the standard method for the diagnosis of GH deficiency is to use radioimmunoassay (RIA) to measure the level of plasma GH in children. For example, basal and stimulated GH concentrations are lower than normal, which can be roughly diagnosed in combination with clinical practice. Four children (6-13 years old) were reported in this paper. One of them had acromegaly and RIA confirmed a lack of GH, but its age, height, weight and annual growth rate (5.8-8 cm