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目的 了解血清肌钙蛋白 T 在急性心肌梗死时的变化。方法 监测急性心肌梗死病人 21 例在梗死后 3 h 至 10 d 和 28 例正常对照的血清肌钙蛋白 T。结果 正常人血清中几乎测不出肌钙蛋白 T,而急性心肌梗死病人在梗死后 3 h 至 10 d 呈不同程度的升高,且升高程度及持续时间均大于 C K、 L D H。结论 血清肌钙蛋白 T 是一项高灵敏度、高度特异反应心肌组织损失及坏死的血清标志物,对诊断急性心肌梗死具有重要的意义。
Objective To understand the changes of serum troponin T in acute myocardial infarction. Methods Serum troponin T was detected in 21 patients with acute myocardial infarction from 3 h to 10 d after infarction and 28 normal controls. Results Serum troponin T was almost undetectable in normal subjects, whereas patients with acute myocardial infarction had different degrees of elevation from 3 h to 10 d after infarction, and the degree of increase and duration were all greater than C K and L D H. Conclusion Serum troponin T is a highly sensitive and highly specific serum marker of myocardial tissue loss and necrosis, which is of great significance for the diagnosis of acute myocardial infarction.