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对41例系统性硬皮病(SS)患者的皮肤评分法加以改良,推出一种新的简单的皮肤评分法。将全身皮肤分为头颈、躯干、手指、上肢、足和下肢7个区域。根据皮肤的厚度和柔韧性分4级:正常为0,增厚为1,捏动度差为2,捏不动为3。评分以该区受累最重部位确定。根据每一区域受累皮肤的范围也分4级:未受累为0,<33％为1,33％～67％为2,>67％为3。上述记分之和即为该患者的皮肤评分。血清Ⅲ型前胶原的氨基末端前肽(PIIINP)以放射免疫法检测。SS则再分为三型:仅肢端硬化未扩展至腕和踝以上为Ⅰ型(限局型),损害扩展至腕、
The skin scoring system was modified in 41 patients with systemic scleroderma (SS) and introduced a new simple skin scoring method. Whole body skin is divided into head and neck, trunk, fingers, upper limbs, feet and lower extremities 7 regions. According to the thickness and flexibility of the skin points 4: Normal 0, thickening of 1, the difference of 2 degrees of pinch, pinching to 3. The score is determined by the most affected area in the area. According to the scope of the affected skin in each region is also divided into four levels: unaffected 0, <33% of 1,33% to 67% of 2,> 67% The sum of the above scores is the skin score of the patient. Amino-terminal propeptide (PIIINP) of serum type III procollagen was detected by radioimmunoassay. SS is subdivided into three types: only acral sclerosis is not extended to the wrist and ankle above type Ⅰ (limited type), damage extended to the wrist,