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将Wistar雄性日龄14天幼鼠复制单侧隐睾(右侧)模型,在日龄28,50和100天时处死,取两侧睾丸。以日龄配对的未手术组和模拟组作对照。结果日龄28天和50天时隐睾组对侧已降睾丸(左侧,contralateraldescendedtestis,CDT)的重量、容积、平均精细管直径(meanaeminiferoustubulediametre,MSTD)和睾丸活检评分(testicularbiopsyscore,TBS)与两个对照组左侧睾丸差异无显著意义(P>0.05)。日龄100天时CDT的重量和容积与两个对照组左侧睾丸差异无显著意义(P>0.05);CDT的MSTD253.5±36.1μm,TBS3.63±0.52分;未手术组和模拟组左侧睾丸的MSTD分别为303.3±17.7μm和303.0±16.6μm,TBS9.58±0.24分和9.6±0.14分,CDT的MSTD和TBS与两个对照组差异有显著意义(P<0.01)。流式细胞计数生殖细胞DNA分析,日龄28天时CDT的两倍体细胞群(diploid,2C)30.08%±9.97%;未手术组左侧睾丸2C75.51%±1.76%,两组差异有显著意义(P?
Male Wistar male 14-day-old pups were unilateral cryptorchid (right) model was sacrificed at 28, 50 and 100 days of age, testis on both sides. Day-paired non-surgical group and control group for the control. Results The weight, volume, mean mesentericoustubulediametre (MSTD) and testicular biopsies (TBS) scores of contralateral descended testis (CDT) in the cryptorchid group with two There was no significant difference in testis between the two groups (P> 0.05). There was no significant difference in the weight and volume of CDT between the two control groups at day 100 (P> 0.05); MSTD253.5 ± 36.1μm and TBS3.63 ± 0.52 at CDT; The MSTD of the testis in the left and right testes were 303.3 ± 17.7μm and 303.0 ± 16.6μm, TBS9.58 ± 0.24 and 9.6 ± 0.14, respectively. The MSTD and TBS of CDT There was significant difference between the two control groups (P <0.01). Flow cytometric analysis of germ cell DNA showed that diploid 2C was 30.08% ± 9.97% of the CDT at day 28, and 2C75.51% ± 1.76% of the left testis in the non-operation group , There was significant difference between the two groups (P?