【摘 要】
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Cardiac sympathetic dysfunction was investigated using 123Imetaiodobenzylguanidine (MIBG) myocardial scintigraphy in 20 patients with drug induced parkinsonism
【机 构】
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Department of Neurology College of Medicine Ajou University Woncheon- dong San 5 Suwon Kyungki- do
【出 处】
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世界核心医学期刊文摘(神经病学分册)
论文部分内容阅读
Cardiac sympathetic dysfunction was investigated using 123Imetaiodobenzylguanidine (MIBG) myocardial scintigraphy in 20 patients with drug induced parkinsonism (DIP). The mean heart to mediastinum ratio was significantly greater in patients with DIP than in those with Parkinson’s disease (mean (SD): 2.07 (0.39) v 1.28 (0.15), p < 0.001). MIBG uptake was not different between the DIP patients and controls. Two DIP patients whose MIBG uptake was significantly reduced showed persistent parkinsonism and responded dramatically to levodopa.
Cardiac sympathetic dysfunction was investigated using 123 Imetaiodobenzylguanidine (MIBG) myocardial scintigraphy in 20 patients with drug induced parkinsonism (DIP). The mean heart to mediastinum ratio was significantly greater in patients with DIP than in those with Parkinson’s disease (mean (SD): 2.07 0.39) v 1.28 (0.15), p <0.001). MIBG uptake was not different between the DIP patients and controls. Two DIP patients whose MIBG uptake was significantly reduced showed persistent parkinsonism and had dramatically to levodopa.
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