本文报告人参根总皂甙的抗遗传毒性效应。利用Ames试验表明人参根总皂甙和人参根乙醇提取物均为鼠伤寒沙门氏菌的非致突变物。在抗FADU试验中,于分离的淋巴细胞加入DNA损伤剂4NQO(2×10~(-5)M)后,分别加入31.25μg/ml和62.50μg/ml的人参根总皂甙,测定其双链DNA比率分别为43.6±5.98和67.3±12.72。与阳性对 This article reports the anti-genotoxic effects of ginseng root saponin. Ames test showed that ginseng root saponins and ginseng root ethanol extract are non-mutagenic Salmonella typhimurium. In the anti-FADU test, 4NQO (2 × 10 -5 M), a DNA damage agent, was added to the isolated lymphocytes, and then 31.25 μg / ml and 62.50 μg / ml of ginseng root saponin were separately added to determine their double-stranded The DNA ratios were 43.6 ± 5.98 and 67.3 ± 12.72, respectively. And positive