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[方法]针对当前农药乳油剂型普遍存在的持效性低与环境污染严重等一系列问题,以乙草胺为芯材,以聚己内酯(PCL)作为壁材,提出采用溶剂提取法制备农药微胶囊和水乳剂的混合剂型。同时,对产品的稳定性、包药率与载药率、释放曲线、尺寸与形貌等进行了表征并考察了制备过程中搅拌速率、温度、表面活性剂、芯壁质量比等因素对产品性能的影响。[结果]混合制剂产品稳定性良好,缓释性能可以达到25 d以上。[结论]与常用的乳油剂型相比,该混合剂型提高了农药利用率与持效性并减少或消除了有机溶剂的使用而降低了环境污染;与微胶囊剂型相比,减少了制备过程中的农药损失,降低了成本。该方法简单易行,成本低廉。
[Method] In order to solve the problems of low maintainability and serious environmental pollution, the current pesticide emulsion formulations are widely used. With acetochlor as the core material and polycaprolactone (PCL) as the wall material, the solvent extraction method Pesticide microcapsules and water emulsion mixed dosage forms. At the same time, the stability of the product, drug-containing rate and drug loading rate, release curve, size and morphology were characterized and the factors such as stirring rate, temperature, surfactant, The impact of performance. [Result] The stability of mixed preparation products was good, and the sustained release performance could reach more than 25 days. [Conclusion] Compared with common cream formulations, the mixed preparation improved pesticide utilization and retention, reduced or eliminated the use of organic solvents and reduced environmental pollution. Compared with microcapsule formulations, The loss of pesticides, reducing costs. The method is simple and low cost.