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Anderson肿瘤中心放疗科对1989—1997年收治的80例转移性直肠癌病人进行分析,所有病人均为腺癌。65%为中分化,20%为低分化。其中男性54例,女性26例;KPS≥80的68例,<80的12例。病人治疗分为两组,第1组55例先行盆腔放化疗后再手术。第2组25例先手术,术后行放化疗。选择手术的病人标准是根据KPS、病灶范围及类型,术前治疗的反应及全身化疗的反应等。83%的病人出现盆腔症状,如出血、梗阻、疼痛、里急后重等。
The Anderson Cancer Center Radiotherapy Division analyzed 80 patients with metastatic rectal cancer who were admitted between 1989 and 1997. All patients had adenocarcinoma. 65% were moderately differentiated and 20% were poorly differentiated. There were 54 males and 26 females; 68 had KPS ≥ 80 and 12 had <80. Patients were divided into two groups. 55 patients in the first group were treated with pelvic radiotherapy and chemotherapy. In the second group, 25 patients were operated first and followed by chemotherapy and radiotherapy. The criteria for selecting patients for surgery are based on KPS, the extent and type of lesions, the response to preoperative treatment, and the response to systemic chemotherapy. Eighty-three percent of patients had pelvic symptoms such as bleeding, obstruction, pain, tenesmus, etc.