烯丙位氧化反应(Allylic Oxidation)通常是指将有机化合物分子中烯丙位上的碳氢键氧化为碳氧键,从而产生醇、醛、酮或酯的过程。通常将生成醇的烯丙位氧化反应,称为“烯丙位羟基化反应”(Allylic Hydroxylation);将生成醛、酮的反应称为“烯丙位羰基化反应”(Allylic Carbonylation);将生成醋酸酯的反应称为“烯丙位乙酰氧基化反应”(Allylic Acetoxylation)。烯丙位氧化反应在有机氧化反应以至于一般有机合成反应中,都具有重要地位。这是因为:a.制备α、β-不饱和醇、醛、酮的经典方法,是采用卤化、水解得到α、β-不饱和醇,如若得到醛、酮则需再进行氧化这样的过程。这样不仅反应步骤长,而且时常伴随发生消除副反应,致使生成的副产物——共轭烯烃一般不易与原料分离,而直接进行烯丙位氧化反应 Allylic oxidation generally refers to the process of oxidation of hydrocarbon bonds in allylic positions in organic molecules to carbon-oxygen bonds to produce alcohols, aldehydes, ketones or esters. The allylic oxidation that usually produces alcohol is termed “Allylic Hydroxylation”; the aldehyde and ketone-forming reaction is referred to as “Allylic Carbonylation” The acetate reaction is called “Allylic Acetoxylation.” Allylic oxidation reaction in the organic oxidation reaction as a general organic synthesis reaction, have an important position. This is because: a. The classic method for preparing α, β-unsaturated alcohols, aldehydes and ketones is by halogenation and hydrolysis to give α, β-unsaturated alcohols. This not only the reaction step is long, and often accompanied by the elimination of side effects, resulting in the formation of by-products - conjugated olefin is generally not easy to separate from the raw material, and direct allylic oxidation reaction