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目的观察肝硬化病人血清甲状腺激素的改变。方法用放射免疫分析法检测30例肝硬化病人和10例健康人的血清甲状腺激素水平，用Child-Pugh积分评价病人的肝功能。结果肝硬化病人血清TT3、TT4、FT3、FT4均明显低于健康人，降低的程度与肝功能损害明显相关，rT3高于健康人，而两者之间TSH水平无明显差异。结论肝硬化常伴有低甲状腺激素水平，且随着肝功能损害的加重而逐渐降低。
Objective To observe the changes of serum thyroid hormones in cirrhotic patients. Methods Serum thyroid hormone levels were measured in 30 patients with cirrhosis and 10 healthy subjects by radioimmunoassay, and their liver function was evaluated by Child-Pugh score. Results Serum levels of TT3, TT4, FT3 and FT4 in patients with cirrhosis were significantly lower than those in healthy people, and the degree of reduction was significantly correlated with liver dysfunction. The level of rT3 in patients with cirrhosis was significantly higher than that in healthy people. There was no significant difference in TSH between the two groups. Conclusions Cirrhosis is often associated with low thyroid hormone levels and decreases gradually with worsening liver function.