乙型肝炎病毒(HBV)感染后临床表现复杂多样,多数表现为急性自限性肝炎,少数表现为暴发性肝衰,还有相当一部分向慢性化发展。在慢性HBV感染中,有的病情较缓和,有的发展迅猛,有的活动期与缓解期交替出现。同为HBV感染,为什么个体表现差异如此之大?以往认为是由机体免疫应答差异引起。但目前的研究认为HBV的基因突变与乙型肝炎(乙肝) Hepatitis B virus (HBV) infection after the complex and diverse clinical manifestations, the majority manifested as acute self-limiting hepatitis, a few showed fulminant hepatic failure, there is a considerable part of the development of chronic. In chronic HBV infection, some of the more moderate conditions, and some rapid development, and some alternating active phase and remission. With HBV infection, why the performance of individual differences so large? In the past that the immune response caused by differences in the body. However, the current study suggests that HBV gene mutations and hepatitis B (hepatitis B)