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目的观察和分析急性心肌梗死介入治疗后用阿托伐他汀强化治疗的效果。方法将2011年6月-2011年12月本院接受PCI治疗的急性心肌梗死患者48例分成两组各24例,实验组术前给予阿托伐他汀80mg,顿服,术后给予40mg,连服1月,qd,之后长期服用20mg,qd;对照组阿托伐他汀20mg,qd,po,长期服用。在术前、术后1月、术后3月、半年对患者进行血液生化检查和随访,观察血脂变化。结果术后3d,实验组CK、CK-MB、LDH均低于对照组,差异有统计意义(P<0.05);术后1月、术后3月及半年实验组TC、LDL-C显著低于对照组,差异有统计意义((P<0.05)。结论对急性心肌梗死患者行PCI治疗,强化阿托伐他汀治疗对心肌可以起到很好的保护作用,对降低血脂,避免急性冠状动脉综合征的复发具有重要意义。
Objective To observe and analyze the effect of intensive treatment with atorvastatin after interventional treatment of acute myocardial infarction. Methods From June 2011 to December 2011, 48 patients with acute myocardial infarction undergoing PCI in our hospital were divided into two groups of 24 patients. The experimental group was given atorvastatin 80mg, In January, qd, after long-term use 20mg, qd; control group atorvastatin 20mg, qd, po, long-term use. Blood biochemical tests and follow-up were performed before surgery, 1 month after surgery, 3 months and 6 months after surgery, and blood lipid changes were observed. Results The levels of CK, CK-MB and LDH in the experimental group were significantly lower than those in the control group on the 3rd postoperative day (P <0.05). The levels of TC and LDL-C in the experimental group at 1 month, 3 months and 6 months after operation were significantly lower (P <0.05) .Conclusion The treatment of atorvastatin in patients with acute myocardial infarction can play a good protective effect on myocardium, and it has a significant effect on lowering blood fat, avoiding acute coronary artery The recurrence of the syndrome is of great importance.