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人类的衰老是一个复杂的生理过程,伴随着衰老相关性疾病的发生,譬如癌症、II型糖尿病、自身免疫性疾病、感染、心脑血管疾病等。其主要发病因素之一是免疫衰退。免疫系统的衰退削弱了机体对肿瘤和病原体的抵抗力,同时增加了自身免疫的风险而引起慢性炎症状态。近十年来,发达国家年龄65岁以上的人群增加了10%以上,预计在2030年超过20%。免疫细胞技术在清除衰老细胞和治疗恶性肿瘤中有明显的作用,为衰老相关性疾病的预防和治疗提供了有效方法。“,”Human aging is a highly complex process that is characterized by an increase in age-associated diseases such as cancer, type 2 diabetes mellitus, autoimmunity, infections, cerebrovascular and cardiovascular disease. One of the common denominators of age-related morbidities is the process of immunosenescence. The aging of the immune system impairs protective immunity against malignant cells and pathogens, but paradoxically increases the risk for autoimmunity to a state of chronic inlfammation. Over the last decade, the proportion of the developed world’s population over the age of 65 years has increased by more than 10%. Furthermore, it is projected to increase further to over 20% by 2030. Immune cell therapy has an obvious effect in the elimination of senescent cells and in the treatment of cancer, and provides an effective method in the prevention and treatment of age-related diseases.