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目的:探讨高血压(HP)伴糖尿病(DM)应用硝苯地平缓释片(NF)治疗的疗效。方法:将94例HP伴DM患者随机分为A组与B组,各47例。两组均常规予以降糖治疗,B组予以厄贝沙坦治疗,A组在B组的基础上加用NF治疗,对比两组的疗效。结果:A组治疗有效率为98.87%,显著高于B组的85.11%(P<0.05);治疗后A组的SBP、DBP显著低于B组(P<0.05),两组的FPG、2h PG、Hb Alc无明显差异(P>0.05)。结论:硝苯地平缓释片辅助治疗HP合并DM能够提高降压效果,改善临床预后,值得推广应用。
Objective: To investigate the efficacy of nifedipine sustained-release tablets (NF) in the treatment of hypertension (HP) with diabetes mellitus (DM). Methods: 94 cases of HP with DM were randomly divided into group A and group B, 47 cases in each. Both groups were routinely given hypoglycemic treatment, group B was treated with irbesartan, group A was treated with NF on the basis of group B, and the curative effect was compared between the two groups. Results: The effective rate of group A was 98.87%, which was significantly higher than that of group B (85.11%, P <0.05). After treatment, the SBP and DBP of group A were significantly lower than those of group B (P <0.05) PG, Hb Alc no significant difference (P> 0.05). Conclusion: The adjuvant treatment of nifedipine sustained-release tablets with DM combined with DM can enhance the antihypertensive effect and improve the clinical prognosis, which is worthy of popularization and application.