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最近几年 ,氟达拉滨成为低度恶性非霍奇金淋巴瘤 (LGNHL)的有效治疗药物。单药应用对以前接受过治疗的患者有效率为 33%~ 5 5 % ,最近的Ⅱ期临床研究发现氟达拉滨与其他药物如环磷酰胺合用效果更好。应用IFN α 2a治疗LGNHL的Ⅱ期临床研究发现 ,IFN α 2a单
Fludarabine has become an effective treatment for low-grade non-Hodgkin’s lymphoma (LGNHL) in recent years. Single-agent regimens have been effective in 33% to 55% of previously treated patients. Recent phase II clinical trials have shown that fludarabine combined with other drugs such as cyclophosphamide works better. Phase II clinical trial of IFNα 2a in the treatment of LGNHL found IFN α 2a single