水稻齿叶矮缩病毒是一种以水稻为侵害寄主的植物呼肠孤病毒 ,其基因组 1 0条dsRNA编码的蛋白质产物的功能除S9外的大部分还未阐明。报道了该病毒菲律宾分离株S8的开放阅读框序列 ,在大肠杆菌中表达和纯化出了其 6 7kD的蛋白质产物 ,并进一步研究了该产物的功能。实验结果表明 ,S8的蛋白质产物是病毒的一种主要结构蛋白质 ,在体外具有自剪切活性和自聚集性质 ,并推测可能是病毒的内层衣壳蛋白 Rice leaf dwarf virus is a plant-borne reovirus with rice as its host. Most of its protein products encoded by the 10 dsRNAs of the genome have not been elucidated except for S9. The open reading frame (ORF) of the isolate S8 from the Philippines was reported, and its 67kD protein product was expressed and purified in Escherichia coli. The function of this product was further studied. The experimental results show that the protein product of S8 is a major structural protein of the virus and has self-shearing activity and self-aggregation property in vitro and is presumed to be the inner capsid protein of the virus