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目的探讨喉声门上型癌双侧颈部淋巴结转移的临床特点及相关因素。方法回顾分析中山大学肿瘤防治中心1992年至2000年收治的180例喉声门上型癌患者的临床病理资料,采用Logistic多元回归分析双侧颈部淋巴结转移相关因素。结果喉声门上癌双侧颈部淋巴结转移率为15.6%,双侧转移率Ⅱ区为53.6%,Ⅲ区为42.9%～50%,Ⅳ区为10.7%,Ⅴ区为3.6%～14.3%。多因素分析显示,原发肿瘤部位和T分期是喉声门上型癌双侧颈部淋巴结转移的相关因素(P<0.05)。结论喉声门上型癌双侧颈部淋巴结转移率较高,主要转移部位为双侧Ⅱ区、Ⅲ区淋巴结;原发肿瘤部位和T分期是喉声门上型癌双侧颈部淋巴结转移的危险因素。
Objective To investigate the clinical features and related factors of cervical lymph node metastases on the laryngeal supraglottic carcinoma. Methods The clinical and pathological data of 180 patients with laryngeal and supraglottic carcinoma admitted to Cancer Center of Sun Yat-sen University from 1992 to 2000 were retrospectively analyzed. Logistic regression was used to analyze the related factors of bilateral cervical lymph node metastasis. Results The rate of bilateral cervical lymph node metastasis on the laryngeal supraglottic carcinoma was 15.6%, the rate of bilateral metastasis was 53.6% in area Ⅱ, 42.9% ~ 50% in area Ⅲ, 10.7% in area Ⅳ and 3.6% ~ 14.3% in area Ⅴ. . Multivariate analysis showed that the primary tumor site and T stage were related factors of bilateral neck lymph node metastasis (P <0.05). Conclusions The rates of bilateral cervical lymph node metastasis on the laryngeal supraglottic carcinoma are high, and the main metastatic sites are bilateral Ⅱ and Ⅲ lymph nodes. The primary tumor site and T stage are bilateral cervical lymph node metastases on the laryngeal and supraglottic carcinoma Risk factors.