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从传统上,全结肠直肠切除和回肠造瘘术是溃疡性结肠炎(UC)的标准治疗,但全结肠、直肠粘膜切除和回肠拉出肛门外直肠吻合(IRA)可保留肛括约肌的功能,作者还对这一手术影响胆盐循环进行了观察。取草原犬作如下分组:1.对照组,6条犬,仅剖腹作胆囊插管造瘘;2.IRA组,7条犬,做胆囊插管造影和IRA;3.ERP组,5条犬,作胆囊插管造瘘,并在IPA的基础上剥除最低部位的5cm直肠粘膜,作8cm长的回肠袋自直肠拉下与肛门吻合。手术后在3～12周内每周取胆囊胆汁作分析。每组有1条犬因并发症未作远期分析。术前、术后6周和12周各抽血作生化检查。
Traditionally, total colorectal resection and ileostomy have been the standard treatment for ulcerative colitis (UC). However, total colon, rectal mucosal resection and pullout of the anorectal anastomosis (IRA) by the ileum preserve the function of the anal sphincter, The authors also observed the bile salt circulation affected by this operation. The dogs were divided into the following groups: 1. control group, 6 dogs, only cesarean section for gallbladder intubation; 2. IRA group, 7 dogs, making gallbladder catheterization and IRA; 3. ERP group, 5 dogs , For gallbladder intubation fistula, and in the lowest part of IPA based on the stripping of 5cm rectal mucosa, 8cm long ileum pouch pulled down from the rectum and anal anastomosis. Gallbladder bile was taken weekly for 3 to 12 weeks after surgery. A group of dogs in each group did not make long-term analysis of complications. Preoperative, postoperative 6 weeks and 12 weeks of blood for biochemical tests.