慢性肾功能衰竭是慢性肾脏疾患晚期的严重的综合症候群,因肾脏排泄和调节功能失常,临床出现许多代谢紊乱的表现,可危及生命。近年来虽已开展血透析治疗,但不能普遍使用,大部分病人仍无满意的治疗方法,故探求更进一步的治疗诚属必要。鉴于尿素氮的降低除通过增加其排除之外,减少蛋白质的动用或增加蛋白质的合成可能有所裨益,故本院自1978年起试用胰岛素治疗,摸索其剂量及给药 Chronic renal failure is a severe syndrome in the late stage of chronic kidney disease. Due to renal excretion and dysregulation, many clinical manifestations of metabolic disorders are manifest and may be life-threatening. Although hemodialysis has been carried out in recent years, it can not be used universally. Most patients are still not satisfied with the treatment, so it is necessary to seek further treatment. In view of the fact that the reduction of urea nitrogen can be of benefit by reducing the use of protein or increasing the protein synthesis by increasing its exclusion, we have tried insulin therapy since 1978 to explore its dosage and administration