论文部分内容阅读
目的探讨妊娠期糖耐量异常妇女产后发生糖代谢异常情况及其影响因素。方法对1998年2月至2005年2月7年间威海市妇女儿童医院妊娠期糖耐量异常妇女446例在产后6～8周进行首次检查,正常者以后每年检查1次,观察项目包括血糖、血脂、体重、血压等。结果产后6～8周检查中,OGTT(口服葡萄糖耐量试验)异常检出率43.27%,与OGTT正常者比较,二者2型糖尿病家族史(T2DM)率、不良孕产史率、诊断孕周差异有统计学意义(P<0.05)。7年间糖耐量异常情况检查中,OGTT异常发生率逐年增高,与OGTT正常者比较,二者2型糖尿病家族史率、高龄率、肥胖率差异有统计学意义(P<0.05)。结论妊娠期糖耐量异常的妇女产后6～8周应再次行糖耐量检查;如无异常及高危因素,产后3年内可免于检查;产后4年开始应进行血糖检查,至少每2年1次;有高危因素者或发现IGT(糖耐量减低)者应每年检查1次。
Objective To investigate the abnormal glucose metabolism in postnatal women with gestational impaired glucose tolerance and its influencing factors. Methods A total of 446 pregnant women with gestational impotence at Weihai Women and Children Hospital from February 1998 to February 2005 were examined for the first time between 6 and 8 weeks postpartum. Normal subjects were checked once a year afterwards. The observation included blood glucose, , Weight, blood pressure and so on. Results The detection rate of OGTT (oral glucose tolerance test) was 43.27% in 6-8 weeks postpartum. Compared with those with normal OGTT, the rates of family history of type 2 diabetes (T2DM), the rate of adverse pregnancy, diagnosis of gestational age The difference was statistically significant (P <0.05). During 7 years, the incidence of OGTT abnormalities increased year by year. Compared with those with normal OGTT, the family history of type 2 diabetes mellitus, elderly rate and obesity rate had significant difference (P <0.05). Conclusion The gestational impaired glucose tolerance in postpartum 6 to 8 weeks should again glucose tolerance test; if no abnormalities and risk factors, postpartum within 3 years from the examination; 4 years after delivery should be carried out blood glucose testing, at least once every 2 years ; Those who are at risk or who have IGT (impaired glucose tolerance) should be tested once a year.