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参与人体免疫应答的体液因子又称之为免疫分子,主要包括免疫球蛋白、补体系统与细胞因子,前二者已为人所熟知,此次主要谈细胞因子(Cytokines)在人体抗癌细胞的作用。 细胞因子除淋巴细胞产生的淋巴因子外,人体内有核细胞产生的免疫因子称之为细胞因子。如单核巨噬细胞、纤维细胞、血管上皮细胞、LGL(LargeGrunlar Lymphocyte)等也产生淋巴样因子样物质,因此在1977年Cohen等命名为单核细咆因子或称细胞因子(Cytokines)。此类物质为非抗体、非补体糖蛋白分子,近年来又发现多肽类生长分化因子。它们有极强的生物活性,微微克即能显示生物活性,很似激素。
Humoral factors involved in the human immune response are also known as immune molecules, mainly including immune globulin, the complement system and cytokines. The former two are well known. This time we mainly talk about the role of Cytokines in human cancer cells. . In addition to cytokines produced by lymphocytes, cytokines produced by human nucleated cells are called cytokines. For example, mononuclear macrophages, fibrocytes, vascular epithelial cells, and LGL (Large Grunlar Lymphocyte) also produce lymphoid factor-like substances. Therefore, in 1977, Cohen et al. named a nuclear factor or a cytotoxin (Cytokines). These substances are non-antibody, non-complement glycoprotein molecules. In recent years, polypeptide growth and differentiation factors have also been discovered. They have a very strong biological activity, micrograms that can show biological activity, very much like hormones.