气道慢性炎症是哮喘发作及反复的病理学的一个主要机制。无论速发型,还是迟发型哮喘,甚至双相型哮喘,病理生理学上均表现为多种炎症细胞相互作用并分泌多种炎症介质和细胞因子,进而在气道浸润和聚集。正是炎症细胞、炎性介质和细胞因子相互作用,才造成气道炎症的持续状态。 Chronic airway inflammation is a major mechanism of asthma attacks and repeated pathologies. Both rapid onset and late-onset asthma, and even bipolar asthma, are pathophysiologically manifested as the interaction of multiple inflammatory cells and the secretion of multiple inflammatory mediators and cytokines that in turn infiltrate and accumulate in the airways. It is the inflammatory cells, inflammatory mediators and cytokines interaction, it caused the continuing status of airway inflammation.