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【目的】观察羟基磷灰石人工骨应用于多节段脊髓型颈椎病(MSCS)后路手术的效果,比较羟基磷灰石人工骨与自体骨的差异。【方法】实施颈椎后路棘突纵切双开门椎管扩大成形术治疗MSCS85例,其中采用自体骨23例,其余62例采用羟基磷灰石人工骨。对比观察手术前后JOA评分及手术用时、术中出血量。【结果】85例患者术后随访>3个月。两组间手术前后JOA评分比较无显著性意义(P>0.05)。采用羟基磷灰石人工骨组手术用时65~110min,平均85.2min;采用自体骨组手术用时75~150min,平均116.4min。采用羟基磷灰石人工骨组术中出血量130~400mL,平均210mL;采用自体骨组手术出血量170~500mL,平均260mL。采用羟基磷灰石人工骨组除3例有羟基磷灰石碎裂外,未发生材料宿主反应及其他严重并发症。【结论】羟基磷灰石人工骨用于治疗MSCS后路手术的效果好,并发症少;手术用时及出血量少。
【Objective】 To observe the effect of hydroxyapatite artificial bone applied to multi-segment myelinated cervical spondylosis (MSCS) posterior surgery and to compare the difference between hydroxyapatite artificial bone and autologous bone. 【Method】 Cervical posterior spinous process was used to treat 85 cases of MSCS. Among them, 23 cases were treated with autogenous bone, and the remaining 62 cases were treated with hydroxyapatite artificial bone. The comparison of JOA score before and after surgery and operation time, intraoperative blood loss. 【Results】 85 patients were followed up for> 3 months. There was no significant difference in JOA score between the two groups before and after operation (P> 0.05). With hydroxyapatite artificial bone group surgery time 65 ~ 110min, an average of 85.2min; with autologous bone group surgery time 75 ~ 150min, an average of 116.4min. The blood loss of hydroxyapatite artificial bone group was 130 ~ 400 mL with an average of 210 mL. The amount of bleeding was 170 ~ 500 mL with an average of 260 mL. With hydroxyapatite artificial bone group in addition to 3 cases of hydroxyapatite fragmentation, no host material reactions and other serious complications. 【Conclusion】 Hydroxyapatite artificial bone is an effective and safe method for the treatment of posterior MSCS with fewer complications.