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自从Blumberg发现乙型肝炎表面抗原以来,对乙型肝炎病毒的抗原抗体系统研究有了很大的进展。到目前为止,人体感染乙型肝炎病毒后,血清内可测得有关5个抗原抗体系统,即:(1)乙型肝炎表面抗原抗体系统;(2)乙型肝炎核心抗原抗体系统;(3)乙型肝炎e抗原抗体系统;(4)乙型肝炎Dane颗粒抗体系统;(5)乙型肝炎δ抗原抗体系统。这5个抗原抗体系统在血清中可测得七项指标,即HBsAg、抗-HBs、抗-HBc、HBeAg、抗-HBe、Dane颗粒抗体和δ抗体。这些指标是乙型肝炎病毒感染的重要标志物。本文就乙型肝炎血清学标志物的临床意义综合于下: 一、乙型肝炎表面抗原抗体系统 HBsAg是感染乙型肝炎病毒后第一个
Since the discovery of hepatitis B surface antigen by Blumberg, much progress has been made in the study of the antigen-antibody system of hepatitis B virus. So far, there are 5 antigen-antibody systems detected in human serum after infection with hepatitis B virus, namely: (1) Hepatitis B surface antigen antibody system; (2) Hepatitis B core antigen antibody system; (3) ) Hepatitis B e antigen antibody system; (4) Hepatitis B Dane particle antibody system; (5) Hepatitis B delta antigen antibody system. These five antigen-antibody systems can detect seven indexes in serum, namely HBsAg, anti-HBs, anti-HBc, HBeAg, anti-HBe, Dane antibody and delta antibody. These indicators are important markers of hepatitis B virus infection. This article on the clinical significance of hepatitis B serological markers integrated in the following: First, hepatitis B surface antigen antibody system HBsAg is the first after infection with hepatitis B virus