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用基因芯片技术比较2型糖尿病大鼠和正常大鼠骨骼肌基因表达谱的差异。糖尿病大鼠有157种基因下调,100种基因上调,部分基因与胰岛素抵抗、糖脂代谢相关。
Gene chip technology was used to compare the gene expression profiles of skeletal muscle between type 2 diabetic rats and normal rats. 157 genes were down-regulated and 100 genes were up-regulated in diabetic rats. Some genes were associated with insulin resistance and glucose and lipid metabolism.