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本研究的目的为观察肠道和肠道外给硝酸甘油(NTG)对血流动力学的效应与门-体分流程度之间的关系。材料和方法:试验以门静脉部分结扎鼠作动物模型(以下称分流鼠),分两组。A组:门静脉部分结扎术后10天(形成明显的门-体分流),从静脉、空肠和门静脉分支等三种途径输注NTG;B组:术后2～10天(形成各种不同程度的门-体分流)经门静脉输注NTG。作颈动脉、颈外静脉、回结肠静脉以及空肠第一个肠襻插管,以测动脉压、门静脉压并用以注药。对照组动物进行同样手术,但不结扎门静脉(以下称假手术鼠)。A组鼠
The purpose of this study was to investigate the relationship between hemodynamic effects of nitroglycerin (NTG) and portal-to-body shunt on intestinal and parenteral nutrition. MATERIALS AND METHODS: The experiment was conducted by partially ligating the rats with a portal vein for animal models (hereinafter referred to as shunts) in two groups. In group A, NTG was infused three times after partial portal vein occlusion (obvious portal-to-body shunt was formed), and NTG was infused through three routes: vein, jejunum and portal vein. Group B: 2 to 10 days after operation Of the door - body shunt) via portal vein infusion of NTG. For the carotid artery, external jugular vein, back to the colon and jejunum bowel first intestinal intubation to measure arterial pressure, portal pressure and injection. Animals in the control group underwent the same procedure but did not ligate the portal vein (hereinafter referred to as sham-operated mice). Group A rats