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一些研究表明头孢氨呋肟(cefuroxime, CXM)治疗产与不产β-内酰胺酶的淋球菌引起的淋病均有效.cefuroxime axetil是CXM酯的药物前体,口服后该酯在肠粘膜水解,吸收良好,外周循环中仅可测得CXM. CXM的抗淋球菌活性及其药物前体的药动学性质表明cefuroxime axetil
Some studies have shown that cefuroxime (CXM) is effective in treating gonorrhea caused by gonococcal bacteria that do not produce β-lactamase.cefuroxime axetil is a prodrug of CXM esters that, after oral administration, hydrolyze in the intestinal mucosa, Absorption is good and only CXM can be measured in the peripheral circulation. The anti-Neisseria gonorrhoeae activity of CXM and the pharmacokinetics of its prodrugs indicate that cefuroxime axetil