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目的观察中药健骨片与非甾体类抗炎镇痛药物(NSAIDs)中西药联用治疗成人大骨节病(KBD)和骨关节炎(OA)患者疗效。方法口服健骨片8周,同时联合NSAIDs治疗成人KBD和OA患者70例,通过治疗前后患者临床体征指标评分,观察药物治疗效果和不良反应。结果 8周后,关节疼痛完全缓解12例,改善54例,另有症状出现反复加重及效果不佳各2例。治疗有效率94.28%,无皮疹、明显胃肠道不适等症状,血常规、肝功指标均在正常范围。结论口服健骨片与NSAIDs中西药联合治疗对成人KBD和OA疗效确定,效果明显,是成人KBD、OA有效治疗方法。
Objective To observe the curative effect of traditional Chinese medicine jiaogu tablet and NSAIDs on treating KBD and OA in adults. Methods Oral bone tablets for 8 weeks, combined with NSAIDs treatment of adult KBD and OA patients 70 cases, before and after treatment by clinical signs score, observe the drug treatment and adverse reactions. Results 8 weeks later, the pain of the joint was completely relieved in 12 cases, improved in 54 cases, and the other symptoms were repeated and the results were poor in 2 cases. Treatment efficiency of 94.28%, no rash, obvious gastrointestinal discomfort and other symptoms, blood, liver function indicators are in the normal range. Conclusion Oral Jianggu tablets and NSAIDs combined treatment of traditional Chinese and Western medicine on adult KBD and OA to determine the efficacy, the effect is obvious, is an effective treatment of adult KBD, OA.