基质金属蛋白酶(matrix metalloproteinases,MMPs)是能降解基质的蛋白水解酶(丝氨酸蛋白酶、半胱氨酸蛋白酶、天门冬氨酸蛋白酶、基质金属蛋白酶)中较为重要的一类。其活性可被体内天然存在的金属蛋白酶组织抑制剂(tissueinhibitors of metalloproteinases,TI MPs)所抑制。二者 Matrix metalloproteinases (MMPs) are the more important class of proteolytic enzymes (serine proteases, cysteine ​​proteases, aspartic proteases, matrix metalloproteinases) that can degrade the matrix. Its activity can be inhibited by the naturally occurring tissue inhibitors of metalloproteinases (TI MPs). both