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树枝状大分子是近年来出现的一类新型合成纳米高分子,具有可控的三维高度支化结构、表面分布着大量的功能基团和单分散等特点,使其在生物医学等领域中日益受到广泛关注。作为一种新型非生物载体,树枝状大分子内部空腔和表面功能基团均可与药物复合,在药物输送和基因转运等方面具有广阔的应用前景。
Dendritic macromolecules are a new class of synthetic nanopolymers that have emerged in recent years. They have controlled three-dimensional hyperbranched structures with a large number of functional groups and monodisperse distribution on the surface, which make them increasingly used in biomedicine and other fields Widespread concern. As a new non-biological carrier, dendrimer’s internal cavity and surface functional groups can be complexed with drugs, which has broad application prospects in drug delivery and gene transfer.