目的:了解广州市城镇居民高血脂症及及其影响因素。方法:选取2015年3月至2015年9月于广州市干部疗养院体检中心进行体检者1 218例作为研究对象,收集一般资料并对体检人群进行体格检查和血清总胆固醇(TC)、甘油三酯(TG)、高密度胆固醇(HDL-C)检测。多因素Logistic回归分析可能影响血脂水平的因素。结果:共纳入1 218名研究对象,TG(1.37±1.02)mmol/L、血浆TC(4.31±1.49)mmol/L、HDL-C(1.22±0.32)mmol/L、空腹血糖(3.76±0.83)mmol/L、收缩压(113.9±15.2)mmHg、舒张压(63.46±10.23)mmHg。单纯性高胆固醇血症、单纯性高甘油三酯血症、混合高脂血症、单纯性低高密度脂蛋白胆固醇血症、高血糖、高血压患病率分别为11.3%、12.2%、4.4%、3.5%、9.4%、9.2%。多因素Logistic回归分析结果显示,高龄、低文化程度、吸烟、饮酒、高血压史、糖尿病史为发生血脂异常影响因素(P<0.05)。结论:血脂异常的发生率较高,高龄、低文化程度、吸烟、饮酒、高血压史、糖尿病史是其主要影响因素。 Objective: To understand the prevalence of hyperlipidemia and its influencing factors in urban residents in Guangzhou. Methods: A total of 1 218 medical examinations were conducted at the medical examination center of Guangzhou cadres’ sanatorium from March 2015 to September 2015. The general data were collected and the physical examination, serum total cholesterol (TC), triglyceride (TG), high-density cholesterol (HDL-C) test. Multivariate logistic regression analysis of factors that may affect blood lipid levels. RESULTS: A total of 1 218 study subjects were enrolled in this study. TG (1.37 ± 1.02) mmol / L, plasma TC (4.31 ± 1.49) mmol / L, HDL-C (1.22 ± 0.32) mmol / L, fasting plasma glucose (3.76 ± 0.83) mmol / L, systolic blood pressure (113.9 ± 15.2) mmHg and diastolic blood pressure (63.46 ± 10.23) mmHg. The prevalence of simple hypercholesterolemia, simple hypertriglyceridemia, mixed hyperlipidemia, simple low-density lipoprotein cholesterol, high blood sugar and hypertension were 11.3%, 12.2%, 4.4 %, 3.5%, 9.4%, 9.2%. Multivariate Logistic regression analysis showed that age, low education level, history of smoking, drinking, history of hypertension and history of diabetes were the influencing factors of dyslipidemia (P <0.05). Conclusions: The incidence of dyslipidemia is high, and the elderly, the low educational level, the history of smoking, drinking, the history of hypertension and the history of diabetes are the main influential factors.