当前,有机化学家面临的合成对象越来越复杂,往往要求在温和的或中性的条件下进行有机合成,近十年来我们在这样的条件下进行了有机合成。“合成控制”是以利用分子间或分子内的相互作用而导致“立体专一”的和熵有利的反应为特点。有机合成中最基本的一些反应,如交叉型的羟醛缩合,分子内和分子间脱 At present, organic chemistry is faced with more and more complex objects, which often require organic synthesis under mild or neutral conditions. In the past decade, we have conducted organic synthesis under such conditions. “Synthetic control” is characterized by an entropy-favorable reaction that leads to “stereospecificity” using intermolecular or intramolecular interactions. Some of the most basic organic reactions, such as cross-type aldol condensation, intramolecular and intermolecular off